Who is suitable for taking albumin?
Albumin (human albumin) is the protein with the highest content in human plasma and has many physiological functions such as maintaining plasma colloid osmotic pressure and transporting nutrients and drugs. In recent years, albumin has become more and more widely used in clinical practice, but not everyone is suitable for use. This article will combine the hot topics and hot content on the Internet in the past 10 days to provide you with a detailed analysis of who is suitable for taking albumin, and provide structured data for reference.
1. The main functions of albumin
Albumin plays the following important roles in the human body:
| Function | illustrate |
|---|---|
| Maintain plasma colloid osmotic pressure | Albumin accounts for 50% to 60% of total plasma protein and is the main substance that maintains plasma colloid osmotic pressure. |
| Transport function | Albumin can combine with a variety of substances, such as hormones, fatty acids, metal ions, etc., to play a transport role. |
| nutritional effect | Albumin acts as a nitrogen source to provide nutrients to tissues. |
| Detoxification | Albumin can bind to certain drugs and reduce their toxicity. |
2. Who is suitable for taking albumin?
Based on clinical guidelines and expert consensus, the following groups may need albumin:
| Applicable people | Specific instructions |
|---|---|
| Severe burn patients | Extensive burns result in a large amount of plasma protein loss, requiring albumin supplementation to maintain blood volume. |
| Patients with cirrhosis and ascites | Patients with liver cirrhosis are often accompanied by hypoalbuminemia, and albumin supplementation can reduce ascites. |
| nephrotic syndrome patients | Albumin may be considered when hypoalbuminemia results from massive proteinuria. |
| acute respiratory distress syndrome (ARDS) | Patients with ARDS may have capillary leakage, and albumin can improve oxygenation. |
| severe septic shock | It may be considered when hypoalbuminemia persists despite adequate fluid resuscitation. |
| perioperative period of major surgery | Albumin supplementation may be considered when hypoalbuminemia occurs before or after major surgery. |
3. Contraindicated groups for albumin
The following groups of people are not suitable for using albumin:
| Taboo groups | reason |
|---|---|
| People allergic to albumin | May cause allergic reactions, severe cases can lead to anaphylactic shock. |
| severe anemia patients | Albumin may increase blood volume and increase the burden on the heart. |
| patients with cardiac insufficiency | Rapid infusion of albumin may cause a sudden increase in blood volume and induce heart failure. |
| Hypertensive crisis patients | Albumin may further increase blood pressure. |
4. Precautions when using albumin
1.Strictly control indications: Albumin is expensive and should be used strictly in accordance with clinical guidelines.
2.Pay attention to the infusion rate: It is generally recommended that the infusion rate of 5% albumin is 1-2ml/min and that of 20% albumin is 1ml/min.
3.Monitor for adverse reactions: Allergic reactions such as fever, chills, and rash may occur. In severe cases, anaphylactic shock may occur.
4.Regularly monitor indicators: Blood pressure, heart rate, urine output, plasma protein levels and other indicators should be monitored during use.
5. Recent hot discussions
In the past 10 days, hot topics about the use of albumin have mainly focused on the following aspects:
| hot topics | Discussion points |
|---|---|
| The role of albumin in the treatment of COVID-19 | There are studies exploring the efficacy of albumin in patients with severe COVID-19 pneumonia. |
| Proper use of albumin | Experts call for avoiding the abuse of albumin and strictly controlling the indications. |
| Albumin replacement research and development | Researchers are developing synthetic alternatives to albumin. |
| Albumin price fluctuations | Albumin supply is tight in some areas and prices fluctuate. |
6. Summary
Albumin is an important blood product suitable for patients with severe burns, cirrhosis, ascites, nephrotic syndrome and other specific diseases. However, albumin is not a universal nutritional supplement and healthy people do not need to supplement it. Abuse may bring risks. When using albumin, medical advice should be strictly followed and adverse reactions should be closely monitored. With the development of medicine, I believe that more safe and effective albumin substitutes will be available in the future.
If you or your family members need to use albumin, it is recommended to consult a professional doctor to develop a personalized treatment plan based on the specific condition. Healthy people can obtain enough protein through a balanced diet and do not need to supplement with albumin.
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